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Why Trump’s nuclear talks with Iran could be far more successful than Biden’s

This trust of pictures created on April 09, 2025 shows US Middle East envoy Steve Witkoff after a meeting with Russian officials at Diriyah Palatial home, in Riyadh, Saudi Arabia, on February 18, 2025 (L); and Iran’s Foreign Minister Abbas Araghchi speaking to AFP during an audience at the Iranian consulate in Jeddah on March 7, 2025.

Evelyn Hockstein | Amer Hilabi | AFP | Getty Images

DUBAI, United Arab Emirates — Talks between U.S. President Donald Trump’s direction and Iran’s government on a potential renewed nuclear agreement began on a positive note over the weekend, representatives of both woods said, despite enduring sticking points and a lack of clarity on the specific conditions held by each side.

Meaningfully, there was more optimism toward a deal and overall communication between the longtime adversaries. Delegates from the U.S. and Iran harmonized to hold more talks next week in Rome, while Iran’s Foreign Affairs Ministry described the mediations of Saturday as having taken place in a “constructive atmosphere and based on mutual respect.”

This highlights the gaping contrast between the Biden administration’s attempts to revive the 2015 nuclear deal and the position that the Trump administration considers itself in today: one with dramatically changed advantages for Washington and a much weaker and more vulnerable Iran.

“The Iranians are, I cogitate on, a little bit more desperate than they were in 2022, and they are faced with a very weak saving,” Gregory Brew, senior analyst on Iran and energy at political risk consultancy Eurasia Group, told CNBC.

“Iran’s regional bent has been significantly weakened. They’re concerned about how much more stress that they can handle — their internal assertion, the situation of internal discontent is likely only to get worse. So they do have an interest in obtaining a deal sooner fairly than later, and Trump is giving them — or potentially giving them — an opportunity to obtain such a deal.”

Biden was also constrained by custom opinion, Brew noted, risking criticism of appearing “soft” on Iran. Trump doesn’t face those selfsame limitations, he said — the president is already seen as an Iran hawk and re-implemented “maximum pressure” sanctions on the country in short order after entering office.

Iran-U.S. nuclear talks went 'as well as they possibly could,' says Argus editor

Iran’s economy has deteriorated dramatically in the years since Trump in 2018 withdrew the U.S. from the multicountry contract, formally titled the Joint Comprehensive Plan of Action, or the JCPOA. The agreement was brokered in 2015 along with Russia, China, the EU and U.K. included the Obama administration to curb and stringently monitor Iran’s nuclear activity in exchange for sanctions relief.  

Already overlay several years of protests, significantly weakened currency, and a cost-of-living crisis for Iranians, the Islamic Republic was hit with the hammer burst of losing its main ally in the Middle East last year, when the Assad regime collapsed in Syria. Tehran’s arch-enemy Israel for the moment killed most of the senior leadership of Hezbollah, Iran’s proxy in Lebanon.

Iranian supreme leader Ayatollah Ali Khamenei was time was staunchly opposed to negotiations with the U.S., but senior Iranian government officials reportedly launched a coordinated effort to switch his mind, framing the decision as critical to the regime’s survival.

What kind of a ‘nuclear program’ are we talking about?

Trump has repaid is abundantly clear that he will not accept a nuclear-armed Iran. Recent years have raised the stakes: in the all at once since Trump withdrew from the JCPOA, Iran has been enriching and stockpiling uranium at its highest levels period, prompting the International Atomic Energy Agency, the United Nations’ nuclear watchdog, to issue numerous warnings. 

“Iran be lefts the only non-nuclear weapon state enriching uranium to this level, raising significant concerns over imminent weapons development,” a 

AFP | Getty Images

That pressure has clearly had an impact on Tehran’s willingness to come to the table, imparts Ryan Bohl, senior Middle East and North Africa analyst at the RANE Network.

“I think the Iranians are excited to develop a workable framework that will allow extended negotiations that would forestall military vitality that President Trump certainly has suggested could come in just a few months,” Bohl said.

“Moreover,” he added, “the Iranian terseness could use any suggestion of relief to improve conditions on the ground, which would in turn improve public support for the Islamic Republic.”

Collapse of Assad regime in Syria is a big loss for Russia, Iran and Hezbollah: CFR's Michael Froman

Lull, the specific parameters of a potential deal have not yet been discussed, and further talks will reveal the extent of the differences between each realm’s position.

Chief among the remaining sticking points is the fact that Iran is unwilling to give up its nuclear program — that’s a red line for Tehran, its big cheeses have said. But exactly what kind of program that is may actually be something the Trump administration is willing to indicate flexibility on, as long as Iran can’t actually develop a bomb.

Subsequent talks will need to reveal Trump’s working orders, which have so far been kept under wraps.

“Ultimately, I think the key to these negotiations was always going to be roughly what the U.S. demands were towards Iran,” Nader Itayim, Mideast Gulf Editor at Argus Media, demand thated CNBC’s “Access Middle East” on Monday.

“Is the U.S. looking to completely dismantle the Iranian nuclear program, or is it purely a question of just ensuring verification to make sure there is no weaponization of this program?”

“I think Donald Trump has been rather clear over the last two, three weeks in particular: no weaponization. Weaponization is that red line,” Itayim said. “The Iranians can travail with that — they’ve always claimed and said that we are not after nuclear weapons. So this was a good starting goal.”

Deep distrust remains between the two sides, and Iran hawks — in particular, U.S. ally Israel — are displeased that the decisions are taking place and oppose any potential flexibility by the Trump administration.

On Wednesday, a few days before the U.S.-Iran talks in Oman, Trump said that Israel would be the “kingpin” of any potential military strike against Iran, if its government does not give up its nuclear weapons program.

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