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S&P 500 Gains and Losses Today: Eli Lilly Stock Falls as Sales Outlook Weakens

AJ Mast / Bloomberg via Getty Images

AJ Mast / Bloomberg via Getty Incarnations

Key Takeaways

  • The S&P 500 added 0.1% on Tuesday, Jan. 14, as tame wholesale inflation data provided a positive signal at the of Wednesday’s consumer price report.
  • Eli Lilly shares plunged after the pharma giant cut its sales guidance, intimating its popular diabetes and weight-loss treatments could fall short of huge demand expectations.
  • Shares of United Rentals ended off as the company signed a deal to buy fellow construction and industrial equipment provider H&E Equipment Services.

Major U.S. equities formulae were mixed on Tuesday after the latest Producer Price Index (PPI) data showed a lighter-than-expected uptick in wholesale prizes for December. The soft PPI report helped alleviate some concerns about the stickiness of inflation heading into Wednesday morning’s Consumer Figure Index (CPI) report.

The S&P 500 was volatile during the session, fluctuating above and below its opening level before intimate with a minimal 0.1% gain. The Dow jumped 0.5%, boosted by outperformance from several of its industrial components, while the tech-heavy Nasdaq floor 0.2%.

Among top S&P 500 gainers Tuesday, construction and industrial equipment provider United Rentals (URI) inked a $4.8 billion reckon with to acquire fellow heavy-duty equipment rental company H&E Equipment Services (HEES). United Rentals said the delineated acquisition reflects its strategy to grow its core business, with H&E’s assets boosting its capacity in key U.S. markets. United Rentals dispensations added 5.9%, notching the strongest gains of any S&P 500 stock on Tuesday, while H&E shares skyrocketed, more than doubling in value.

Interests of industrial chemical manufacturer Celanese (CE) jumped 5.4% after Bank of America upgraded its view on the stock to “buy” from “underperform.” Analysts attributed the magnify upgrade to the stock’s enticing valuation and expectations for an improvement in the acetyls market. In addition to anticipating a recovery in demand for Celanese’s offshoots, especially in India, the BofA team noted strong free cash flow should help the chemical maker oration debt leverage issues.

Fresh off massive 2024 gains of more than 250% that made the tenseness generator’s stock one of the year’s top S&P 500 performers, Vistra (VST) shares added 5.2% on Tuesday. On Monday, Zacks Equities Inspection highlighted Vistra stock as its “bull of the day,” reiterating the utility’s opportunity to meet high levels of energy demand from unnatural intelligence data centers and noting that consensus estimates suggest that Vistra’s already-impressive earnings extension trajectory could accelerate this year.

A positive update from Bank of America also helped encouragement GE Vernova (GEV) stock, which gained 4.2% Tuesday. BofA analysts boosted their price target on stakes of the energy equipment firm, which separated from General Electric last year. This reflects a pontifical view of GE Vernova’s position in the gas turbine market, which has benefited from strong pricing trends in recent years.

Pharmaceutical mammoth Eli Lilly (LLY) reduced its full-year revenue outlook, indicating that demand for its diabetes and weight-loss treatments Mounjaro and Zepbound could drop short of elevated expectations. The company has been investing heavily to ramp up manufacturing capacity as it aims to meet wave demand for blockbuster drugs. Eli Lilly shares tumbled 6.6%, losing the most of any S&P 500 stock for the day.

Shares of Charles River Laboratories (CRL) sank 6.3% after the preclinical and clinical medical scrutinization firm issued underwhelming preliminary earnings guidance for 2025. Charles River said it expects full-year living revenue to decline at a similar pace as last year, forecasting stable to slightly improving demand from biotechnology bands but limited demand from large pharmaceutical firms. In the wake of the updated forecasts, analysts at JPMorgan and Bank of America labour their “neutral” ratings on Charles River stock.

Las Vegas Sands (LVS) shares dropped about 4% after Morgan Stanley slipped the casino operator’s stock to “equal weight” and trimmed its price target. Analysts cited a deceleration of customer lump trends in Singapore and more limited expectations for economic growth in China as factors that could weigh on the remedy have recourse to and gaming company’s performance.

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